We recently had our monthly meeting with our Parents as Teachers provider and during our session I mentioned something that has been on my mind for months…”I feel like a pioneer in regards to children with Fragile X Syndrome and partial methylation.”
Fragile X Syndrome is the leading known genetic cause of autism and intellectual disabilities worldwide; however, when parents start looking for answers regarding their child’s behavior and development the odds are if their child is given an autism diagnosis they do not do any type of genetic testing. I am NOT here to tell you what to do, but I do want to help inform you on other possible contributing factors that might help your family even more.
When a child goes to the doctor for an Autism Screening, they are assessing your child’s behavior and development. Most of the time, doctors are hesitant to make a diagnosis in a child younger than 18 months. If a child does receive a diagnosis of Autism, that is usually where things end regarding tests/answers. Parents take that diagnosis and work on next steps to help their child get the therapies and support they need, which is amazing! The one thing I want to stress here, is that there could be a genetic reason as to why your child has Autism.
Here are some stats from FragileXAwareness.com.
Number of carriers of the Fragile X premutation
- Approx 1 in 468 Men
- Approx 1 in 151 Women
Number with the full mutation of Fragile X
- Approx 1 in 3,600 to 4,000 males
- Approx 1 in 4,000 to 6,000 females
- Approx 1 in 3 with Fragile X also have Autism
The last bullet is what I want to call out, 1 in 3 with Fragile X also have Autism! For me being adopted, genetic testing made total sense for us to do. Even knowing my biological parents didn’t uncover me being a carrier for Fragile X Syndrome. The other piece to a genetic syndrome/disorder is that some skip generations and some expand as they are passed down to the next generation, so while a parent might not show signs of something, it doesn’t mean that their child couldn’t have something.
If something seems off with your child’s development/behavior, it might be beneficial to ask about genetic testing too. The more informed you are, the better equipped you are to help your child and yourself. As I am a carrier for Fragile X, there are also things I need to be aware of; FXPOI, characterized as early menopause, decreased ovarian function, or irregular cycles. There are Social-Emotional Effects; increased risk for depression, anxiety and social anxiety. Males have to worry about FXTAS, Fragile X Associated Tremor/Ataxia Syndrome.
The more you know!
XOXO
